Thrombospondin type-1 domain-containing 7A—a new player in membranous nephropathy
نویسندگان
چکیده
منابع مشابه
Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Autoantibodies against M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A), which mainly belong to the IgG4 subclass, were reported as associated antibodies for the development of MN. Although PLA2R is a major target antigen for idiopathic MN, the prevalence of MN patient...
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ژورنال
عنوان ژورنال: Nature Reviews Nephrology
سال: 2014
ISSN: 1759-5061,1759-507X
DOI: 10.1038/nrneph.2014.227